Cannabidiol is a widely utilized natural treatment for a variety of things.
CBD stands for cannabidiol, and it is one of over 100 chemical compounds found in the cannabis or marijuana plant, Cannabis sativa (R1).
The psychoactive cannabinoid tetrahydrocannabinol (THC) is the major psychoactive cannabinoid contained in cannabis. It is what gives you that “high” feeling. CBD, on the other hand, is not psychotropic like THC.
It is a good choice for people who want to get relief without the mind-altering effects of marijuana, or other pharmaceutical medicines.
The oil is manufactured by extracting CBD from marijuana plants. Then, diluting it with a carrier oil such as coconut or hemp seed oil.
It’s gaining popularity in the health and wellness industry. Some scientific research indicating that it can help with symptoms of chronic pain and anxiety.
Here are seven reasons backed with published science we think you should know before you try CBD Oil.
CBD & Pain Relief
Since 2900 B.C., marijuana has been used to relieve pain (R2).
Scientists have recently discovered that some components of marijuana, such as CBD, are responsible for its pain-relieving properties.
Endocannabinoids are neurotransmitters produced by the body that connect to cannabinoid receptors in the nervous system.
CBD has been demonstrated to alleviate chronic pain by influencing endocannabinoid receptor function, decreasing inflammation, and interacting with neurotransmitters, according to research (R4).
For example, one rat study discovered that CBD injections lowered pain response to surgical incisions, while another rat study discovered that CBD treatment reduced sciatic nerve pain and inflammation considerably (R5, R6).
A combination of CBD and THC has been demonstrated to be useful in relieving pain associated with multiple sclerosis and arthritis in several human studies.
Sativex, an oral spray containing THC and CBD. Has been licensed in numerous countries to alleviate pain associated with multiple sclerosis.
A one-month study of 47 persons with multiple sclerosis looked at the effects of using Sativex. Pain, walking, and muscle spasms all improved for the subjects. Nonetheless, there was no control group in the trial, and placebo effects cannot be ruled out (R7).
In another trial, 58 persons with rheumatoid arthritis reported that Sativex dramatically decreased pain during movement, discomfort during rest, and sleep quality (R8).
In conclusion, CBD, particularly when combined with THC, may be useful in lowering pain associated with disorders such as multiple sclerosis and rheumatoid arthritis.
2. CBD For Anxiety and Depression
Anxiety and depression are two frequent mental health illnesses that can have serious consequences for one’s health and well-being.
According to the World Health Organization, depression is the leading cause of disability globally, with anxiety disorders ranking sixth (R9).
Anxiety and depression are typically treated with pharmacological medicines, which can produce sleepiness, agitation, sleeplessness, sexual dysfunction, and headaches (R10).
Furthermore, some drugs, such as benzodiazepines, can be addictive and lead to substance dependence (R11).
CBD oil has shown potential as a treatment for both depression and anxiety, sparking the curiosity of many people who suffer from these conditions.
In one Brazilian study, 57 males were given either CBD or a placebo 90 minutes before taking a simulated public speaking test.
A 300-mg dose of CBD was determined to be the most effective at considerably lowering anxiety during the test by the researchers.
The placebo, a 150-mg CBD dose, and a 600-mg CBD dose had little to no effect on anxiety (R12).
CBD oil has even been used to treat sleeplessness and anxiety in youngsters suffering from post-traumatic stress disorder in a safe manner (R13).
These properties are related to CBD’s ability to operate on serotonin receptors in the brain, a neurotransmitter that affects mood and social behavior.
To conclude, in both human and animal research, CBD has been demonstrated to alleviate anxiety and depression.
3. Can CBD Really Alleviate Cancer-Related Symptoms
CBD may aid in the reduction of cancer-related symptoms as well as cancer-related adverse effects such as nausea, vomiting, and pain.
One study examined the effects of CBD and THC on 177 persons suffering from cancer-related pain who had not found relief from pain medication.
When compared to individuals who received simply THC extract, those who received an extract containing both components saw a considerable reduction in discomfort (R16).
CBD may also aid in the reduction of chemotherapy-induced nausea and vomiting, which are two of the most prominent chemotherapy-related adverse effects for cancer patients (R17).
Though there are medications available to aid with these painful symptoms, they are not always helpful, prompting some people to seek alternatives.
A study of 16 chemotherapy patients discovered that a one-to-one combination of CBD and THC delivered through mouth spray reduced chemotherapy-related nausea and vomiting better than standard treatment alone (R18).
CBD has even been found in animal and test-tube experiments to have anti-cancer effects. One test-tube study, for example, discovered that concentrated CBD caused cell death in human breast cancer cells (R19).
In another study, CBD was shown to suppress the spread of aggressive breast cancer cells in mice (R20).
However, because they are test-tube and animal research, they can only speculate on what might work in humans. More human investigations are required before conclusions may be drawn.
While CBD has been proven to help alleviate symptoms associated with illness and cancer therapy, and may even have cancer-fighting capabilities, further research is needed to determine its efficacy and safety.
4. Amazing Skin Benefits (OUT OF THIS WORLD)
Acne is a widespread skin ailment that affects about 9% of the population (R21).
It is assumed to be caused by a combination of factors, including heredity, bacteria, underlying inflammation, and an overproduction of sebum, an oily secretion produced by the skin’s sebaceous glands (R22, R23).
According to recent scientific research, CBD oil may aid in the treatment of acne due to its anti-inflammatory effects and capacity to lower sebum production.
In one test-tube investigation, CBD oil stopped sebaceous gland cells from secreting excessive sebum, acted as an anti-inflammatory agent, and inhibited the activation of “pro-acne” chemicals such as inflammatory cytokines (R24).
Another study found similar results, indicating that CBD may be an effective and safe strategy to treat acne, owing to its amazing anti-inflammatory properties (R25).
Though these findings are encouraging, further research into the benefits of CBD on acne is required.
Summary CBD may be effective for acne because of its anti-inflammatory properties and capacity to reduce sebaceous gland overproduction.
5. My favorite, Might Have Neuro-protective Properties
CBD’s potential to act on the endocannabinoid system and other brain signaling systems, according to researchers, may give benefits for persons suffering from neurological illnesses.
Indeed, one of the most researched CBD applications is in the treatment of neurological illnesses such as epilepsy and multiple sclerosis. Despite the fact that research in this area is still in its early stages, numerous studies have yielded encouraging results.
Sativex, a CBD and THC oral spray, has been shown to be a safe and effective technique to relieve muscle stiffness in persons with multiple sclerosis.
According to one trial, Sativex reduced spasms in 75% of 276 persons with multiple sclerosis who had medication-resistant muscle spasticity (R26).
Another trial administered 0.9–2.3 grams of CBD oil per pound (2–5 g/kg) of body weight to 214 persons with severe epilepsy. The seizures were reduced by 36.5 percent on average (R27).
Another study discovered that CBD oil, when compared to a placebo, dramatically reduced seizure activity in children with Dravet syndrome, a complicated pediatric epilepsy illness (R28).
It is crucial to note, however, that some patients in each of these studies suffered adverse effects from CBD medication, such as convulsions, fever, and exhaustion.
Cannabidiol Neurological Illness
CBD has also been studied for its potential efficacy in treating a variety of other neurological illnesses.
Furthermore, animal and test-tube studies have suggested that CBD may reduce inflammation and aid in the prevention of neurodegeneration linked with Alzheimer’s disease (R31).
Researchers fed CBD to rats genetically susceptible to Alzheimer’s disease in one long-term trial and discovered that it helped prevent cognitive deterioration (R32)
To conclude CBD has been demonstrated to provide a number of benefits, despite the fact that current research is restricted.
Epilepsy and Parkinson’s disease symptoms could be relieved. CBD was used to treat a variety of ailments.
In test-tube and animal studies, it has also been found to slow the progression of Alzheimer’s disease.
6. Heart Benefits?
CBD has been related to many circulatory system benefits, including the ability to decrease high blood pressure, according to recent studies.
High blood pressure has been related to an increased risk of a variety of health problems, including stroke, heart attack, and metabolic syndrome (R33).
CBD has been shown in studies to aid with high blood pressure.
A recent study demonstrated that giving nine healthy males 600 mg of CBD oil lowered resting blood pressure when compared to a placebo.
The guys were also given stress tests, which are known to raise blood pressure. Surprisingly, the men’s blood pressure increased less than expected in response to these tests after just one dose of CBD (R34).
CBD’s ability to help lower blood pressure may be due to its stress- and anxiety-relieving qualities, according to research.
Furthermore, because of its significant antioxidant and stress-reducing qualities, CBD has been shown in multiple animal studies to help reduce the inflammation and cell death associated with heart disease.
One study indicated that treating diabetic mice with heart disease with CBD lowered oxidative stress and avoided heart damage (R35).
In conclusion, while additional human research is needed, CBD may enhance heart health in a variety of ways, including lowering blood pressure and preventing heart damage.
7. Other Possible Benefits
Other than the health conditions listed above, CBD has been explored for its function in treating a variety of ailments.
CBD is thought to provide the following health benefits, though further research is needed:
CBD may assist people with schizophrenia and other mental disorders by lowering psychotic symptoms, according to research (R36).
Treatment for substance abuse: CBD has been demonstrated to alter brain circuits linked to drug addiction. CBD has been demonstrated to lessen morphine addiction and heroin-seeking behavior in mice (R37).
CBD has been shown to have anti-tumor properties in both test tubes and animals. It has been demonstrated to stop the spread of breast, prostate, brain, colon, and lung cancer in animals (R38).
Diabetes prevention: CBD therapy lowered the incidence of diabetes in diabetic mice by 56% and greatly reduced inflammation (R39).
In conclusion, some research suggests that CBD may aid in the treatment of diabetes, substance misuse, mental problems, and some malignancies.
However, a further human study is required.
None of this has been approved by the FDA and we do not want you to use this to treat, cure, or prevent any disease.
This article was to cite the studies done and help people get a perspective of where we stand in the science aspect of CBD knowledge.
There Can Be Side Effects
CBD is generally well tolerated and considered harmless, however, some people may experience negative side effects.
The following are some of the side effects that have been reported in studies: (R40):
- Appetite and weight fluctuations
This is especially crucial if you’re using any drugs or supplements that include a “grapefruit warning.” Grapefruit and CBD both inhibit cytochromes P450 (CYPs), a family of enzymes involved in drug metabolism (R42).
CBD-rich cannabis extracts have the potential to cause liver damage, according to a mouse study. However, several of the animals in the study were given unusually high dosages
(600mg/kg) of the extract by force (R43).
To summarize everything, Although CBD is usually regarded harmless, some people may have side effects such as diarrhea and lethargy. Certain drugs may also be affected.
CBD oil has been researched for its possible involvement in reducing the symptoms of a variety of common health problems, including anxiety, depression, acne, and heart disease.
It may potentially provide a natural alternative for pain and symptom treatment for cancer patients.
CBD oil is still being studied for its possible health advantages, so new therapeutic applications for this natural treatment are bound to emerge.
Though there is still much to understand about CBD’s efficacy and safety, new research suggests that CBD could be a safe and effective natural treatment for a variety of ailments.
If you want to try CBD, there are a variety of products available online, including candies, oils, and lotions.
Is CBD a legal substance? CBD products made from hemp (with less than 0.3 percent THC) are legal in the United States, however, they are still banned in several states.
CBD products produced from marijuana are prohibited on the federal level, although they are lawful in several states.
Check the laws of your home state as well as the laws of any country you visit.
It’s important to remember that nonprescription CBD products aren’t FDA-approved and may be mislabeled, though we put extensive tests on our companies to ensure purity per dose.