Does CBD Work

Does CBD work?

By now you probably know what CBD is and have a friend or coworker using it. You’re probably like me at first and your skeptical about it’s worth, and if it even works. I know I like to research before I buy into a fad or new product that floods the markets. What if it’s all a sham, what if there’s no science behind it. Fortunately, that’s not the case with CBD and I’ll reference some studies to prove it.

One of CBD’s biggest claim to fame and actual worthiness of being helpful with problems is seizures. The FDA has two approved CBD syrup drugs for 3 rare seizure conditions. Mind you this isn’t even “Full Spectrum” CBD. Most of these studies being done are with the isolated form of CBD. When you’re reading about the synergy effect, know I strongly believe that all the cannabinoids are worth their weight in gold. The terpenes are just an amazing icing on the cake that can change the flavor or direction dramatically. For the sake of argument since these studies are all done on the isolation of the molecule lets say for now that it doesn’t entirely matter.

Even more interestingly since the decade before 2012, only 3 studies had been published on any Cannabis Medicinal Research. Since then, around 30 have been published. The consensus is that there needs to more studies conducted before they have all the facts. What have they found? Let’s dive in.


Let’s just start with a study from the European Journal of Pain, showing evidence that CBD applied topically to animals could help with pain and inflammation associated with Arhrietous. Another study showed that the mechanism CBD inhibits inflammatory and neuropathic pain. Witch in the medical industry is two of the most difficult types of chronic pain to manage. The science behind it is quite incredible, but I’m kind of a nerd. I like it when they find a receptor in the brain that no one would even think to look at can actually help manage pain. The most notable study done was by San Diego’s Center for Medicinal Cannabis Research. It showed cannabis cigarettes reduced pain by up to 40%. With the placebo only topping a 20% mark for a reduction in pain.

Sleep and Anxiety

In a large case study done, posted here, 103 Adults were tested. They had tests done when at baseline and after the CBD treatments were done. The final test had 72 patients left and they saw a 79% reduction in anxiety in just the first month. Sleep scores also improved in the first month at around 66% of the test studies though those numbers did fluctuate. This test was done and posted to the US National Library of Medicine National Institutes of Health. Out of the 103 patients, only three responded badly to the CBD. The amounts used were around 300mg – 600mg and though they did feel a reduction in anxiety they also had sedative effects at that high of a dose. In addition to endorphin release, the “runner’s high” after exercise has shown to induced in part by anandamide acting on CB1 receptors, eliciting anxiolytic effects on the body. The activity of CBD at 5-HT1A receptors may drive its neuroprotective, antidepressive, and anxiolytic benefits, although the mechanism of action by which CBD decreases anxiety is still unclear.

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