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CBD Answered by a Pharmacist

What Is CBD?

You have probably heard CBD mentioned somewhere. CBD is a hot topic in articles, news, and advertisements. Even food products now contain CBD. So we decided why not get answers about CBD Answered By A Pharmacist

CBD is an acronym for cannabidiol, which is the major cannabinoid found in cannabis. It is a natural compound extracted from the plant Cannabis sativa. CBD is naturally absorbed in the body’s endocannabinoid system. Upon reaching the brain the compounds don’t fully attach with neurons in the endocannabinoid system. Unlike THC, CBD goes to both the CB1 and CB2 which helps in dealing with things like pain and stress management to immune function, sleep management, and hormone regulation. As cannabinoids are found in the body naturally, so CBD oil is quite effective in dealing with several illnesses and ailments because the body naturally absorbs and accepts them.

Research into the human body shows the existence of an endocannabinoid system that is present in the body has been proved by researches.  Some researchers also believe that the endocannabinoid system has an important role in the body’s homeostasis. This research has led to the discovery of two endocannabinoid receptors in the human body – CB1 and CB2 – that potentially help in reducing pain and anxiety, inducing relaxation, and assist with blood pressure control.

How Does CBD Work In The Body?

Scientists are constantly trying to find out how exactly CBD works in the body. Although many scientists agree on the fact that CBD doesn’t work on the CB1 and CB2 receptors, but rather that CBD is responsible for protecting anandamide.  Anandamide is the chemical that activates the receptors which produce the positive effects associated with the endocannabinoid system.

Currently, CBD has only been approved by FDA to use for the treatment of two rare forms of childhood seizures, but studies are being done to check what else CBD is capable of. CBD also has been proved useful for treating inflammation and pain, anxiety, PTSD, epilepsy, multiple sclerosis, graft vs, Crohn’s disease, host disease, and autoimmune disorders. 

Will CBD Make Me Feel “High?”

CBD extracted from marijuana is not legal in all states because the cannabis plant contains higher amounts of THC, which makes you high – and lower levels of CBD. However, CBD extracted from hemp (cannabis Sativa) makes it completely non-psychoactive, meaning it won’t get you high because it contains higher amounts of CBD with little to no THC. 

When you consider CBD for use, the ratio between CBD and THC makes the difference. CBD derived from hemp contains less than 0.3 % THC, while CBD derived from marijuana contains 5 to 30 % THC.

If people with chronic diseases want to get the health benefits from CBD without getting high should purchase hemp-derived CBD oils that contain less than 0.3 %  THC or entirely THC-free oil.

There are many questions like How Much CBD Should I Take?? What Are The Side Effects Of CBD Therapy? Can I Take CBD Instead of My Other Medications? in people’s minds.

Let’s address one question at one time.

How Much CBD Should I Take?

Except for Epidiolex which is an FDA-approved CBD product, there are no recommended dosages of CBD. Scientists and doctors don’t yet know what dosage and doses will work best for different conditions. Despite this, studies have shown that a single dose of up to 6000 mg results in very few negative side effects.

What Are The Side Effects Of CBD Therapy? 

The most common side documented in studies include nausea, fatigue, weight loss, diarrhea, and difficulty in sleeping, but many people reported no side effects at all.

Current researches on how  CBD works in the body points to twice-daily dosing of oral forms of the drug. Studies have revealed that oral forms of CBD are best absorbed by the body when taken with a high-calorie or high-fat meal. It is not recommended, it is just what primary researches have shown. Always take advice from your doctor or pharmacist before any CBD regimen.

Can I Take CBD Instead of My Prescriptions?

Some people have started taking CBD instead of prescribed medicines having high hopes that CBD will be more effective. It is very important to remember that CBD available over the counter is not a suitable replacement for prescription medications.

Despite having the benefits of CBD, it is not yet approved by FDA to cure, diagnose or treat any disease except Epidiolex for seizures. CBD is not held to have the same benefits and safety standards that prescription medicines have.

Are There Any Interactions Between Prescription Drugs And CBD? 

When it comes to CBD people think that it is a natural product that does not have any side effects and has no interaction with prescription drugs. This is not the fact. Likewise many other medications, CBD is also metabolized by the liver which means it can have interaction with the body’s natural system and can also interact with prescribed drugs.  

Prescripted medications and the other supplements you take that action with CBD might, therefore, be present in your body in raised or minimized amounts than what they’re meant to be. Why will this matter? Reckoning on the medication and also the interaction, you may be in danger of experiencing a lot of aspect effects or not obtaining the total advantages of your medication.

Since CBD is metabolized by the liver, so it is not suitable for people with liver problems. Again, CBD has not yet been fully studied, so there may be still more drug interactions that we do not know about.

Known CBD Interactions:

  • CBD can increase the body’s levels of warfarin, citalopram, and other drugs that can depress central-nervous-system, including some anti-seizure medications.
  • CBD can also decrease the levels of clopidogrel in the human body.
  • CBD levels can also be affected by other drugs.  

Is CBD Approved by FDA? 

Although, Farm Bill 2018 has legalized the CBD products derived from heme still law has continued to be fuzzy. CBD in cosmetics and topical forms – such as topical sprays, creams, ointments, salves, etc are legal. CBD is also legal as a prescription drug called Epidiolex, which means, although it is available everywhere over-the-counter, CBD products in oral supplement form are still technically illegal.

It is extremely important to beware of the companies and products that claim that CBD can do wonders and can treat anything. As mentioned earlier CBD is only approved by FDA to treat two kinds of seizures. And any other company claiming that CBD can treat anything else, are making false and illegal claims. 

While I was doing my research into CBD product lines and companies, I saw a few brands claiming that CBD can cure cancer. It is not only yet has been proven but it is also illegal for the company to make such claims about their products.

Beware Of Mislabelled Products 

Another thing to be taken into account is some products are mislabelled. That means they do not contain the amount that is mentioned on their labels. In 2016 a research was done to find out how accurately the companies label their products that were available over the internet. 84 kinds of different products were tested including vaping liquids, oils, and tinctures obtained from 31 different companies

A shocking report came with 69% of the examined products were mislabeled –  either they contain less or more than the amount labeled. Only 31% of products were accurately labeled.

To avoid buying such mislabeled products, see if the company has a Certificate of Analysis for their products. COA recognized brands can provide you the exact information about their products that how much CBD and other chemicals their product contain. CBD products that have COA also mention when was the product testing is done and the date of manufacturing of each product. We at Connected Healing take this process very seriously and you’ll notice this as we roll out new products and part ways with others.

What A Pharmacist Thinks You Should Know About CBD

Here are some of the key points that CBD-curious people should know: 

  • Only one product has been approved by the FDA which is called Epidiolex. It is used for treating two types of seizures. Otherwise, CBD products are not yet approved to treat or cure, any other diseases. Currently, there are many potential uses of CBD being studied by researchers but are not FDA approved yet.
  • Do not start taking CBD products as a replacement for your prescripted medications. It could be dangerous for your health.  
  • Always make sure the CBD product that you are getting is coming from a reliable source. Be aware of the mislabeled products and companies out there claiming about the contents of their products and what CBD can do. 
  • CBD has many potential drug interactions. Ask your doctor if you are intended to use any CBD-based product and you on any prescribed medications.

 Conclusions About CBD

I am sure everybody is seeing a lot of advertisements online claiming that CBD is a new miracle that can cure all without side effects. I wish it would be true but there is not enough evidence to prove that it can treat anything. Some known side effects should be taken into account before using CBD-based products.

However, CBD is being used for many other purposes and we are studying it every day. It’s not wrong to say that shortly we will have a better understanding of CBD and how it works in the body leading to more legitimate uses for it, which is an exciting aspect!

 

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